POLIOVIRUS TRAFFICKING TOWARD CENTRAL NERVOUS SYSTEM VIA HUMAN POLIOVIRUS RECEPTOR-DEPENDENT AND -INDEPENDENT PATHWAY.

Poliovirus trafficking toward central nervous system via human poliovirus receptor-dependent and -independent pathway.

In Clip Set humans, paralytic poliomyelitis results from the invasion of the central nervous system by circulating poliovirus (PV) via the blood-brain barrier (BBB).After the virus enters the central nervous system (CNS), it replicates in neurons, especially in motor neurons (MNs), inducing the cell death that causes paralytic poliomyelitis.Along w

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Phylogenetic and morphological discord indicates introgressive hybridisation in two genera of Australian millipedes (Diplopoda, Polydesmida, Paradoxosomatidae)

Discord between molecular and morphological datasets was observed in two pairs of species of Australian millipedes in the family Paradoxosomatidae using morphological and molecular phylogenetic analysis Clip Set (mitochondrial COI rDNA and 16 rRNA, and nuclear 28S rRNA).Close to the presumed distributional boundary between Pogonosternum nigrovirgat

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Studying the cellular basis of small bowel enteropathy using high-parameter flow cytometry in mouse models of primary antibody deficiency

BackgroundPrimary immunodeficiencies are heritable defects in immune system function.Antibody deficiency is the most common form of primary immunodeficiency in humans, can be caused by abnormalities in both the development and activation of B straight razor cells, and may result from B-cell-intrinsic defects or defective responses by other cells re

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